Himalaya 180 Rumalaya forte + 6 Rumalaya gel

Himalaya 180 Rumalaya forte + 6 Rumalaya gel

Rumalaya forte helps rebuild connective tissue and alleviates the discomfort caused by impaired movement. Arthritis and joint pain discomfort is a widespread occurrence that can result from such factors as climate, lifestyle, work habits, or repetitive movement. Taken daily, Rumalaya forte has demonstrated positive results in relieving pain due to various conditions, including arthritis, osteoarthritis, back pain, frozen shoulder and other joint conditions.

Rumalaya Forte tablet is useful for the treatment of:

• Rheumatoid arthritis
• Osteoarthritis
• Cervical and lumbar spondylosis
• Traumatic inflammatory conditions like fibrositis, bursitis, synovitis, capsulitis, tenosynovitis, myositis and sciatica
• Arthralgia
• Gout
• Frozen shoulder

Composition     
Rumalaya forte tablet contains:

Powders:

    Shallaki (Boswellia serrata)     240mg
      Guggulu Suddha (Commiphora wightii)     200mg
      Rasna (Alpinia galanga)     70mg
      Yashti-madhu (Glycyrrhiza glabra)     70mg
Extracts:

    Gokshura (Tribulus terrestris)     60 mg
    Guduchi (Tinospora cordifolia)     60mg
 

.     Shallaki (Boswellia serrata)     240mg

      Guggulu Suddha (Commiphora wightii)     200mg

Habitat
Occurs in the arid rocky tracts of Rajputana, Khandesh, Berar, Mysore, Sind and Baluchistan. Morphology Description (Habit) A small tree or shrub with spinescent branches. The leaflets are 1-3 in number and obovate. The ash-coloured bark comes off in rough flakes exposing the underbark which also peels off in thin papery rolls.
Principal Constituents
The commercial product contains about 4.65% foreign matter and about 1.45% of an aromatic essential oil besides gum and resin. Guggul or the gum resin from the bark contains the octanordammarane terpenes manusumbionic acid and manusumbinone .
Pharmacology
The ethyl acetate extract of Commiphora mukul was found to confer significant protection to albino rats against the development of experimental atherosclerosis. The drug not only prevented deteriorating changes in serum cholesterol, triglycerides, and plasma fibrinogen level but also favorably increased plasma fibrinolytic activity. The oleoresin fraction of guggulu possesses significant anti-arthritic and anti-inflammatory activities, the minimum effective dose being 12.5mg./100 g. body weight. The crude aqueous extract of the oleo gum resin was found to suppress acute rat-paw edema induced by carrageenin. It also had a suppressive action against the granuloma pouch test. In adjuvant arthritis, the extract suppressed the secondary lesions very effectively without having any significant action on the primary phase. Side effects such as gastric ulceration, loss of weight and mortality were negligible in the animals treated with the extract as compared to those treated with betamethasone.
Clinical Studies
Clinical trial with purified guggulu (Commiphora mukul) has been carried out in 35 patients of rheumatoid arthritis in order to assess its antirheumatic activity, dose requirement, resistance development, side effects, and effects on hematology (ESR). From the results obtained it has been indicated that guggulu acts as a digestive and analgesic agent without any toxic or side effects. Twenty patients of hyperlipidemia were administered 4.5 g. of purified gum guggulu in two divided doses daily for 16 weeks. Serum cholesterol and serum triglyceride levels decreased at the end of the 4th and 8th weeks. HDL cholesterol showed a gradual increase while VLDL and LDL cholesterol showed significant decrease at all time points.
Toxicology
Some adverse side-effects reported on taking guggul are mild diarrhea and nausea. It may possibly raise bilirubin levels, cause hemolysis of blood, hepatitis, and obstruction of the biliary tract. But these side effects need to be confirmed.
Indications
It is astringent, anti-inflammatory and antiseptic. When taken internally it acts as a bitter, stomachic and carminative, stimulating the appetite and improving digestion. It causes an increase in leucocytes in the blood and stimulates phagocytosis. It acts as a diaphoretic, expectorant and diuretic, and is said to be a uterine stimulant and emmenagogue. The resin is used in the form of a lotion for indolent ulcers and as a gargle in chronic tonsilitis, pharyngitis and ulcerated throat.

      Rasna (Alpinia galanga)     70mg

      Yashti-madhu (Glycyrrhiza glabra)     70mg

Habitat
It grows in the sub- tropical and warm temperate regions of the world, chiefly in Mediterranean countries and China. Morphology Description (Habit) It is a hardy herb or undershrub; the leaves are multifoliolate, imparipinnate; the flowers are in axillary spikes, papilionaceous, lavender to violet in colour; the pods are compressed and contain reniform seeds. The rootstock, which is stout, throws off a large number of perennial roots. The dried, peeled or unpeeled underground stems and roots constitute the drug known in the trade as Licorice.
Principal Constituents
The principal constituent of liquorice to which it owes its characteristic sweet taste is glycyrrhizin, which is present in different varieties in a concentration of 2-14%. This principle is not found in the aerial parts of the plant. Other constituents present in liquorice are: glucose (up to 3.8%), sucrose (2.4-6.5%), mannite, starch ( 30% ), asparagine, bitter principles, resins (2-4%), a volatile oil (0.03-0.035%) and coloring matter. The yellow color is due to the anthoxanthin glycoside, iso liquiritin which, undergoes partial conversion to liquiritin during drying and storage of roots. Iso liquiritin gives on hydrolysis iso liquiritigenin, while liquiritin gives liquiritigenin as a glucone. Both iso liquiritin and liquiritin are bitter with a sweet after-taste and stimulate the salivary glands. Commercial samples contain c. 2.2% of iso liquiritin. A steroid estrogen, possibly estriol, is also reported to be present in liquorice. The presence in the inner bark of a hemolytically active saponin has been reported. The plant contains phytoestrogens in the form of isoflavones such as formononetin; glabrone, neoliquiritin and hispaglabridin A & B.
Pharmacology
Glycyrrhizin, a glycoside obtained from G. glabra was studied for its anti-arthritic and anti-inflammatory effect on formaldehyde induced rat-paw edema in adrenalectomised rats. It was found to potentiate the anti-arthritic action of hydrocortisone in rats.
Clinical Studies
The oral administration of the powdered root of G.glabra in 5 cases of pemphigus, who had been kept free from the bullae with prednisolone, could considerably reduce the dose of prednisolone without the reappearance of the lesions. The potentiating effect of G.glabra appeared to be due to its inhibitory effect on the metabolic degradation of predn