Zandopa is an herbal remedy for the treatment of Parkinson’s disease from Zandu Pharmaceuticals, India. The product is a water-soluble powder sourced from a plant called ‘Mucuna pruriens’ which contains a natural source of Levodopa. This should be taken with water and milk is contraindicated.
It is a standardized, safe, effective & economical natural source of levodopa which can effectively replace Synthetic L-dopa formulations in patients who comply with its dosage regimen. It is free from all side effects of regular synthetic L Dopa and also will improve the overall functions of the body.
Zandopa powder has been used in India for hundreds of years for several arthritic disorders, sexual weakness, and nervous disorders. The presence of natural levodopa was identified a couple of decades back.
Ayurvedic formulation derived from the seeds of Mucuna pruriens.
The long history of use in Ayurvedic Medicine for CNS disorders &also as a geriatric tonic.
Richest known source of L-dopa.
Effective in the treatment of Parkinson’s
disease.
Offers predictable efficency.
Suitable for long-term use
Readily bio-available & better tolerated.
Crosses the blood-brain barrier easily as compared
to synthetic L-dopa
Composition
Each 7.5 gm contains standardised processed seed powder of Mucuna pruriens Bak (6.525 gm in a flavored base)
Better compliance due to better tolerence or
lesser side effects.
Cost effective
What is the best medication for Parkinson’s disease?
The seed powder of the leguminous plant, Mucuna pruriens has long been used in traditional Ayurvedic Indian medicine for diseases including parkinsonism. The pharmacological action of Zandopa is due to the action of levodopa on the brain. Evidence indicates that symptoms of Parkinson’s disease are related to the depletion of stratal dopamine activity in basal ganglia.
Levodopa is the metabolic precursor of dopamine and unlike dopamine can cross the blood-brain barrier. Once in the brain, it is decarboxylated to form dopamine.
Zandopa improves all the signs and symptoms of Parkinsonism. Bradykinesia responds first followed by rigidity and tremors. Improvement of these primary neurological symptoms is accompanied by a similar improvement in overall functional ability. Secondary motor symptoms such as disturbance in posture, gait, associated movements, facial expression, speech, handwriting, swallowing, and respiration are also prominently improved.
It also favorably influences the psychic behaviors producing a sense of well-being, an increased interest in self and surroundings. After initial treatment regimen, the beneficial effects of Zandopa can be maintained for prolonged periods by smaller maintenance dose.
The clinical studies with mucuna seed powder suggests that this natural souce of L-dopa might possess advantages over conventional L-dopa preparations in the long term management of Parkinson’s disease. (J Neurol Neurosurg Psychiatry. 2004)
When should I take Zandopa powder?
As directed by the physician. In Half a glass of water (approx – 100ml) suspend the prescribed dose powder, stir, and drink immediately.
Precautions
All known precautions and contraindications as applicable to synthetic L-DOPA formulations should also be followed while prescribing Zandopa.
Is Zandopa safe?
Side effects as encountered with synthetic L-DOPA formulations have not been seen to the same severity, however the same may be observed in some patients taking large doses of Zandopa.
Safety
Long-term safety studies conducted in laboratory animals have not shown any serious toxicity with this product & in doses as high as 10% of the diet.
Caution
• Store in a cool dry place.
• Protect from light.
• Keep the continer tightly closed.
• Keep out of reach of children.
• Not to be taken with milk.
